Other Hormone Replacement Therapy Dosage Forms

I want to briefly highlight two of the less frequently requested options: vaginal suppositories and topical liquids.

Vaginal suppositories are often used in cases where a more localized route of delivery is desired. They are similar in purpose to vaginal creams but may be preferred in certain situations based on patient and provider preference. One practical advantage of suppositories is that the dosing is easy to track—each unit is individually prepared and clearly countable. However, because they are designed to soften or melt at body temperature, they should be stored properly to avoid melting in warm environments.

Topical HRT liquids are another available form, though less common today. These are typically applied to the skin using a measured syringe and rubbed in until absorbed. While straightforward in terms of preparation and use, this form can sometimes leave a residue on the skin or other surfaces it contacts. That said, topical liquids may be considered in certain cases based on formulation needs and cost considerations.

Every dosage form has pros and cons, and the best option will vary depending on patient goals, preferences, and prescriber recommendations. If you’re curious about these or other compounded HRT options, we’d be happy to discuss them further.

We’re available in the compounding lab Monday through Friday, 9 a.m. to 5 p.m., or you can reach me directly at brandon.ladage@belewdrugs.com.

Until next time,Brandon

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Compounding

*Compounded medications are prepared by prescription to meet the individual needs of patients and are not evaluated or approved by the FDA. This content is for informational purposes only and is not intended to diagnose, treat, or cure any condition. Always consult your licensed healthcare provider before making decisions about treatment or medications.